生物学・生命科学・基礎医学

• Dynamic evolution of retroviral envelope-derived sequences in primates

  Koichi Kitao、Kirill Kryukov、Lihua Jin、Yuta Shintaku、Takashi Hayakawa、Nakagawa, So

  • endogenous retrovirus
  • de novo genes
  • co-option
  • primate evolution

  ダウンロード ：48 - 投稿日時:2025-11-29 08:23:44 UTC - 公開日時:2025-12-01 09:27:55 UTC

  • PDF (English)
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  • Supplement-3_XLSX (English)
  • Supplement-4_XLSX (English)
  • Supplement-5_XLSX (English)
  • Supplement-6_XLSX (English)
  • Supplement-7_XLSX (English)

• AI-Powered Predictive Analytics for Early Detection of Cardiovascular Diseases Using Electronic Health Records A Retrospective Cohort Study

  Ying, Zhang、Sun Xin

  • artificial intelligence
  • cardiovascular diseases
  • predictive analytics
  • electronic health records
  • early detection
  • deep learning

  ダウンロード ：45 - 投稿日時:2025-10-29 02:44:08 UTC - 公開日時:2025-11-14 10:24:33 UTC

  • PDF (English)

• シナヌマエビにおける環境色に対応した体色変化の検証

  井芝, 悠貴、武中, 綾之介、佐藤, 伶於、中山, 惺太、福家, 悠介

  • 色環境
  • 背景同化
  • DNAバーコーディング
  • RGB輝度値

  ダウンロード ：88 - 投稿日時:2025-10-29 23:43:51 UTC - 公開日時:2025-11-04 07:19:10 UTC

  • PDF

• Aging, disease and transcriptomic liberality derived from human RNA-seq data

  Norichika OGATA

  • Liberality

  ダウンロード ：46 - 投稿日時:2025-10-17 12:02:59 UTC - 公開日時:2025-10-24 01:30:43 UTC

  • PDF (English)

• オオムラサキ交尾行動の野外観察記録

  中, 信子

  • オオムラサキ
  • Sasakia charonda
  • 交尾行動
  • 求愛行動
  • 行動観察

  ダウンロード ：38 - 投稿日時:2025-09-19 06:40:17 UTC - 公開日時:2025-10-21 00:58:35 UTC

  • PDF

• Amino‑acid composition is a selection target for coding‑sequence retention: evidence from out‑of‑frame translation comparisons in Escherichia coli

  Genshiro Esumi

  • Amino‑acid composition
  • Amino‑acid composition space
  • De novo gene
  • Reference proteome
  • Mutual‑constraint hypothesis

  ダウンロード ：78 - 投稿日時:2025-09-30 05:27:25 UTC - 公開日時:2025-10-06 02:30:36 UTC

  • PDF (English)

• EVALUATION OF THE EFFECT OF PTYCHOPETALUM OLACOIDES (MUIRA PUAMA) EXTRACT ON ALUMINIUM CHLORIDE-INDUCED NEUROTOXICITY IN RATS.

  Joshua Ajao、Akinsanmi Akinsehinwa、Olakunle Onaolapo、Adejoke Onaolapo

  • Aluminium Chloride
  • Muira puama
  • Neurotoxicity
  • Neuroinflammation
  • Neuroprotection

  ダウンロード ：62 - 投稿日時:2025-09-11 19:53:24 UTC - 公開日時:2025-09-22 10:18:18 UTC

  • PDF (English)

• Verification of questionable information about the COVID-19 vaccines

  Takeshi Nitta、Taku Kashiyama、Yoshihisa Matsumoto、Tetsuya Toyoda、Takayuki Miyazawa、Yukari Kamijima、Kakeya, Hideki

  • COVID-19
  • mRNA vaccines
  • Self-amplifying RNA vaccines
  • DNA contamination
  • Genomic integration
  • Vaccine safety

  ダウンロード ：959 - 投稿日時:2025-08-06 09:10:31 UTC - 公開日時:2025-09-11 07:32:52 UTC

  • PDF (English)

• TaKoHigh enables accurate variant calling and phasing of PCR-based long-read sequencing data

  Yuka Eura、Atsushi Takahashi、Sheng Ye、Kazuya Sakai、Masanori Matsumoto、Koichi Kokame

  • long-read sequencing
  • PCR amplicons
  • variant calling
  • haplotype phasing
  • chimeric reads
  • ADAMTS13
  • thrombotic thrombocytopenic purpura

  ダウンロード ：89 - 投稿日時:2025-09-06 07:18:53 UTC - 公開日時:2025-09-10 08:22:28 UTC

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  • Supplement-1_PDF (English)
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• YIPFα1A expression is regulated by multilayered molecular mechanisms

  Tokio Takaji、Yurika Nakanishi、Nobuhiro Nakamura

  • Golgi
  • complex formation
  • mRNA stability
  • codon adaptation index
  • 3′ untranslated region

  ダウンロード ：54 - 投稿日時:2025-09-02 07:21:47 UTC - 公開日時:2025-09-09 01:09:22 UTC

  • PDF (English)

• 酵母細胞におけるヒト細胞質スーパーオキシドジスムターゼ1による小胞体ストレス惹起

  Ngoc Trang Nguyen、木俣（石渡）, 有紀、細見, 昭、木俣, 行雄

  • 神経変性疾患
  • 異常蛋白質応答
  • サッカロミセス・セレビジエ

  ダウンロード ：71 - 投稿日時:2025-09-01 11:11:50 UTC - 公開日時:2025-09-02 09:56:24 UTC

  • PDF (English)

• Discovery of NOT-GPCRs: An Archaeal Membrane Protein Family Whose AlphaFold Predictions Structurally Resemble G Protein-coupled Receptors

  Sakuma, Koya

  • Marine Group II (MGII)
  • Bacteriorhodopsin (bR)
  • G protein-coupled receptor (GPCR)
  • Data mining
  • Structure–function relationship
  • AlphaFold2

  ダウンロード ：226 - 投稿日時:2025-08-01 18:43:23 UTC - 公開日時:2025-08-07 04:24:37 UTC

  • PDF (English)
  • Supplement_XLSX (English)

• Cholangiocarcinoma in a cat infected with domestic cat hepatitis B virus

  Haruka Dosaka、Nanami X Kato、Kei Taga、Soshin Yamamoto、Kaito Kondo、Rissar Siringo Ringo、Yasuyuki Kaneko、Takuya Hirai、Akatsuki Saito、Fuke, Naoyuki

  • cat
  • cholangiocarcinoma
  • domestic cat hepadnavirus
  • immunohistochemistory
  • in situ hybridization

  ダウンロード ：230 - 投稿日時:2025-07-10 05:46:40 UTC - 公開日時:2025-07-14 09:59:36 UTC

  • PDF (English)
  • Supplement_WORD (English)

• カメラトラップで撮影した野生動物の観察記録データセットの作り方：国際標準形式 Camera Trap Data Package（Camtrap DP）解説

  寺山, 佳奈、戸津, 久美子、深澤, 圭太

  • 自動撮影装置
  • データパッケージ
  • 野生動物

  ダウンロード ：150 - 投稿日時:2025-07-04 00:42:51 UTC - 公開日時:2025-07-04 08:27:55 UTC

  • PDF

• Fish-Hunting by Wild Japanese Macaques in Riverine Environments: Behavioral and Demographic Patterns with Implications for Sex-Invariant Foraging in Early Hominins

  Ayaka Tsuchihashi、Takuya Matsumoto、Ema Nagahara、Kosuke Hayashi、Genki Yamada、Takayuki Ogura、Mone Ito、Shohei Isokado、Koji Tojo、Masaki Takenaka

  • mountain ecology
  • hunting
  • primatology
  • Japanese macaques
  • human evolution
  • sex differences

  ダウンロード ：191 - 投稿日時:2025-06-03 02:03:08 UTC - 公開日時:2025-06-20 04:45:28 UTC

  • PDF (English)

• Unraveling the Nutritional Significance of Essential Amino Acids through Synthesis Cost and Cellular Allocation

  Genshiro Esumi

  • Essential amino acids
  • Amino acid synthesis cost
  • Economical Evolution
  • Differential Recycle Efficacy Framework
  • Allocation-Derived Significance Hypothesis

  ダウンロード ：145 - 投稿日時:2025-06-04 01:26:40 UTC - 公開日時:2025-06-06 07:38:12 UTC

  • PDF (English)

• Anxiety-causing alleles may confer evolutionary advantages not in very dangerous but in moderately stressful environments

  Kenta Motoyashiki、Motohide Seki

  • 5-HTTLPR
  • Depression
  • Anxiety
  • Evolutionary medicine
  • Mathematical biology
  • VMAT1

  ダウンロード ：125 - 投稿日時:2025-05-20 06:12:17 UTC - 公開日時:2025-05-28 00:17:05 UTC

  • PDF (English)
  • Supplement_PDF (English)

• A Complementary Perspective on the Evolutionary Emergence of Essential and Non-Essential Amino Acids

  Genshiro Esumi

  • Essential Amino Acids
  • Non-Essential Amino Acids
  • Metabolic Optimization
  • Compartmentalization
  • Differential Recycle Efficacy Framework

  ダウンロード ：289 - 投稿日時:2025-05-11 05:14:39 UTC - 公開日時:2025-05-19 02:41:26 UTC

  • PDF (English)

• Upright Light-Sheet Microscopy with Two-Photon Excitation for Imaging Large Samples

  Takashi Saitou、Sota Takanezawa、Ryosuke Kawakami、Kana Kobayashi-Taguchi、Mai Kamito、Kana Takemoto、Yosuke Niko、Yuji Tsukamoto、Ryotaro Ozaki、Atsushi Tsurumune、Yoshiaki Kamei、Yuzo Umeda、Takeshi Imamura

  • Fluorescence imaging
  • Light-sheet microscopy
  • Two-photon excitation
  • in vivo imaging
  • Optical clearing

  ダウンロード ：277 - 投稿日時:2025-05-01 01:30:00 UTC - 公開日時:2025-05-01 09:41:49 UTC

  • PDF (English)

• Not Only Residue Amino Acid Composition but Also Gene Thymine–Adenine Balance Reflect Protein Hydropathy

  Genshiro Esumi

  • Hydropathy
  • TA skew
  • Nucleotide composition
  • Genetic code
  • Chargaff’s second parity rule
  • Optimized translation hypothesis

  ダウンロード ：184 - 投稿日時:2025-03-18 05:24:54 UTC - 公開日時:2025-03-24 06:17:03 UTC

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• Forest thinning has little effect on the spatiotemporal dynamics of arbuscular mycorrhizal fungi community in Cryptomeria japonica roots

  DJOTAN, Akotchiffor Kevin Geoffroy、Norihisa Matsushita 、Yosuke Matsuda、Kenji Fukuda

  • Forest management
  • Thinning
  • AMF ecology
  • Metabarcoding
  • Spatiotemporal distribution

  ダウンロード ：180 - 投稿日時:2025-03-18 02:54:02 UTC - 公開日時:2025-03-19 01:47:55 UTC

  • PDF (English)

• Why Is Tyrosine, More Abundant in Intracellular Proteins, Classified as a Non-Essential Amino Acid?: The Extracellular Demand Hypothesis

  Genshiro Esumi

  • Extracellular Demand Hypothesis
  • Extracellular Protein Hypothesis
  • Amino acid synthesis
  • Tyrosine
  • Evolution

  ダウンロード ：192 - 投稿日時:2025-02-03 04:47:53 UTC - 公開日時:2025-03-04 09:53:33 UTC

  • PDF (English)

• Development of bioluminescent Switchbody, antigen-triggered enzyme switch and elucidation of its principle

  Takanobu Yasuda、Yoshiyuki Ueno、Masahiko Taguchi、Naoya Tochio、Hiromasa Yagi、Shuma Yazaki、Ryoichi Arai、Bo Zhu、Takanori Kigawa、Hiroshi Ueda、Kitaguchi, Tetsuya

  • protein switch
  • homogeneous immunoassay
  • X-ray structural analysis
  • solution NMR
  • MD simulation

  ダウンロード ：388 - 投稿日時:2025-02-19 08:01:14 UTC - 公開日時:2025-02-25 01:11:21 UTC

  • PDF (English)
  • Supplement-1_PDF (English)
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• 鶏卵（タマゴ）は多細胞真核生物にとって共通した実質的なエクソーム適合食（Exome Matched Diet）である

  江角, 元史郎

  • エクソーム適合食
  • 鶏卵
  • アミノ酸組成
  • 食品成分組成
  • 栄養学

  ダウンロード ：292 - 投稿日時:2025-01-23 08:08:19 UTC - 公開日時:2025-01-30 08:25:15 UTC - バージョン：2

  • PDF_ver.2 (English)

• The Gene’s GC Content Is the Greatest Source of Inter-Species Differences in Protein Amino Acid Composition

  Genshiro Esumi

  • Amino acid composition
  • GC content
  • TA skew
  • Species Difference
  • Diversity

  ダウンロード ：119 - 投稿日時:2025-01-27 00:32:42 UTC - 公開日時:2025-01-28 10:19:23 UTC

  • PDF (English)
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