Pathogenicity of sublineage BA.5, omicron variant strain comparison with other variant strains of SARS-Cov-2 and seasonal influenza in Japan: Updated until January 2023
DOI:
https://doi.org/10.51094/jxiv.59Keywords:
excess mortality, COVID-19, all cause death, stochastic frontier estimation, NIID model, Tokyo, JapanAbstract
Background: Sublineage BA.5 of omicron variant strain recorded the highest peak of morbidity and mortality confirmed with test per day in August for the former and September for the latter, 2022.
Object: We sought to quantify excess mortality using the National Institute of Infectious Diseases (NIID) model for all cause of death to evaluate pathogenicity of sublineage BA.5 of omicron variant strain.
Method: We applied the NIID model to deaths of all causes from 1987 up through the January, 2023 for the whole of Japan and up through October, 2022 for Tokyo.
Results: Results in Japan show that 18845, 14133, 8300, 6702, 18426 and 18404 excess mortality was observed in August 2022 to January 2023,which means 16.8, 13.0,7.0 , 13.7 and 12.7 % of the baseline and approximately 74% of total excess mortality during the COVID-19 pandemic. Even in Tokyo, it was 3742 and 36% of total of excess mortality in this pandemic, between August and October, 2022.
Discussion and Conclusion: Results may indicate that its pathogenicity was much stronger than other variant strain and seasonal influenza.
Conflicts of Interest Disclosure
No author has any conflict of interest, financial or otherwise, to declare in relation to this study.Downloads *Displays the aggregated results up to the previous day.
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Submitted: 2022-04-27 04:32:31 UTC
Published: 2022-05-02 09:17:47 UTC — Updated on 2023-03-31 08:14:48 UTC
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The study period has been extended.License
Copyright (c) 2022
Junko Kurita
Tamie Sugawara
Yasushi Ohkusa
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
