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Preprint / Version 4

Pathogenicity of sublineage BA.5, omicron variant strain comparison with other variant strains of SARS-Cov-2 and seasonal influenza in Japan: Updated until August 2022.

##article.authors##

  • Junko Kurita Department of Nursing, Faculty of Sport and Health Science, Daito Bunka University
  • Tamie Sugawara Infectious Disease Surveillance Center, National Institute of Infectious Diseases
  • Yasushi Ohkusa Infectious Disease Surveillance Center, National Institute of Infectious Diseases

DOI:

https://doi.org/10.51094/jxiv.59

Keywords:

excess mortality, COVID-19, all cause death, stochastic frontier estimation, NIID model, Tokyo, Japan

Abstract

Background: Sublineage BA.5 of omicron variant strain recorded the highest peak of morbidity and mortality confirmed with test per day in August for the former and September for the latter, 2022.

Object: We sought to quantify excess mortality using the National Institute of Infectious Diseases (NIID) model for all cause of death to evaluate pathogenicity of sublineage BA.5 of omicron variant strain.

Method: We applied the NIID model to deaths of all causes from 1987 up through the August, 2022 for the whole of Japan and up through June, 2022 for Tokyo.

Results: Results in Japan show that 18845 excess mortality was observed in August 2022,which means 16.8% of the baseline and almost 40% of total excess mortality during the COVID-19 pandemic.

Discussion and Conclusion: Results may indicate that its pathogenicity was stronger than other variant strain and seasonal influenza.

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Sugawara T, Ohkusa Y. Comparison of Models for Excess Mortality of Influenza Applied to Japan. Journal of Biosciences and Medicines, 2019, 7, 13-23. doi:10.4236/jbm.2019.76002

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Submitted: 2022-04-27 04:32:31 UTC

Published: 2022-05-02 09:17:47 UTC — Updated on 2022-11-14 06:52:08 UTC

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Reason(s) for revision

The study period has been extended.
Section
General Medicine, Social Medicine, & Nursing Sciences