プレプリント / バージョン1

Influential Force: from Higgs to the Ab Initio Genetic Orbital Method


  • Mori, Tsutomu Department of Human Lifesciences, Fukushima Medical University School of Nursing
  • Takashi Kawamura Department of Human Lifesciences, Fukushima Medical University School of Nursing
  • Daisuke Ikeda Kitajima-cho, Itano-gun
  • Susumu Goyama Division of Molecular Oncology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo
  • Hiroshi Haeno Medical Mathematical Modelling Laboratory, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo
  • Kazuhiko Ikeda Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University
  • Katsue Adachi Chi Co., Ltd.
  • Yoshihiko Saito Chi Co., Ltd.
  • Tomoyoshi Horisawa Chi Co., Ltd.
  • Junzo Suzuki Fukushima Preservative Service Association of Health
  • Seiichi Takenoshita Fukushima Medical University




influential force、 unification theory、 Higgs mechanism、 ab initio genetic orbital method、 immune checkpoint


Nature has a tendency to evolve to a more probable state, and we regard this tendency as a force of probability. All fundamental interactions are transmitted by mediator particles, and their unification has long been attempted. However, no theory has fully unified the interactions into a single simple formula. Here, we show that fundamental interactions are unified by a novel “influential force” driven by probability under the canonical distribution of the transmitted information. This force affects the information distance denoting transmission difficulty, based on a universal gauge symmetry within information coordinate spacetime. We develop statistical mechanics of mutual information and reveal that the influential force exists in both physical and biological systems, offering clues to solve many intractable problems. In the field of physics, the influential force provides a coherent explanation of the spontaneous symmetry breaking of the Higgs field and its relationship with gravity, inflation, quantum entanglement entropy, and the hierarchy problem. In the field of biology, the force endows genes with huge network information, which leads to the development of the ab initio genetic orbital method and identification of a novel immune checkpoint, KYNU / kynureninase. Our findings demonstrate that the influential force acts between highly divergent beings, thereby shaping the essential properties of nature.

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投稿日時: 2022-09-05 15:16:26 UTC

公開日時: 2022-09-07 23:26:28 UTC