Sleep and quiet wakefulness signify an idling brain hub for creative insights

Mostafa R. Fayed; Khaled Ghandour; Kaoru Inokuchi

doi:10.51094/jxiv.671

##article.authors##

Mostafa R. Fayed Research Centre for Idling Brain Science, University of Toyama https://orcid.org/0000-0002-2142-8204
Khaled Ghandour Research Centre for Idling Brain Science, University of Toyama https://orcid.org/0000-0002-7354-7918
Kaoru Inokuchi Research Centre for Idling Brain Science, University of Toyama https://orcid.org/0000-0002-5393-3133 https://researchmap.jp/kaoruinokuchi?lang=en

DOI:

https://doi.org/10.51094/jxiv.671

キーワード:

Memory、 Engram、 Sleep、 Idling brain、 Reactivation、 Inference

抄録

Long-term potentiation of synaptic strength is a fundamental aspect of learning and memory. Memories are believed to be stored within specific populations of neurons known as engram cells, which are subsequently reactivated during sleep, facilitating the consolidation of stored information. However, sleep and offline reactivations are associated not only with past experiences but also with anticipation of future events. During periods of offline reactivation, which occur during sleep and quiet wakefulness, the brain exhibits a capability to form novel connections. This process links various past experiences, often leading to the emergence of qualitatively new information that was not initially available. Brain activity during sleep and quiet wakefulness is referred to as the "idling brain". Idling brain activity is believed to play a pivotal role in abstracting essential information, comprehending underlying rules, generating creative ideas, and fostering insightful thoughts. In this review, we will explore the current state of research and future directions in understanding how sleep and idling brain activity are interconnected with various cognitive functions, especially creative insights. These insights have profound implications for our daily lives, influencing our ability to process information, make decisions, and navigate complex situations effectively.

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The authors declare no conflict of interest (COI)

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