The missing link between autoimmune diseases and microchimerism

Acién, P., Acién, M., Ruiz-Maciá, E., & Martín-Estefanía, C. (2014). Ovarian teratoma-associated anti-NMDAR encephalitis: a systematic review of reported cases. Orphanet journal of rare diseases, 9(1), 1-9.

Aggarwal, S., & Pittenger, M. F. (2005). Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood, 105(4), 1815-1822.

Allen, L. A., & Aderem, A. (1996). Molecular definition of distinct cytoskeletal structures involved in complement-and Fc receptor-mediated phagocytosis in macrophages. The Journal of experimental medicine, 184(2), 627-637.

Amur, S., Parekh, A., & Mummaneni, P. (2012). Sex differences and genomics in autoimmune diseases. Journal of autoimmunity, 38(2-3), J254-J265.

Anderson, N. E., & Barber, P. A. (2008). Limbic encephalitis–a review. Journal of Clinical Neuroscience, 15(9), 961-971.

Arnaiz, S. L., Llesuy, S., Cutrín, J. C., & Boveris, A. (1995). Oxidative stress by acute acetaminophen administration in mouse liver. Free Radical Biology and Medicine, 19(3), 303-310.

Baker, H. G., Clarke, G. N., McGowan, M. P., Koh, S. H., & Cauchi, M. N. (1985). Increased frequency of autoantibodies in men with sperm antibodies. Fertility and sterility, 43(3), 438-441.

Banales, J. M., Sáez, E., Úriz, M., Sarvide, S., Urribarri, A. D., Splinter, P., ... & LaRusso, N. F. (2012). Up‐regulation of microRNA 506 leads to decreased Cl−/HCO3− anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis. Hepatology, 56(2), 687-697.

Bednarska, N. G., Wren, B. W., & Willcocks, S. J. (2017). The importance of the glycosylation of antimicrobial peptides: Natural and synthetic approaches. Drug Discovery Today, 22(6), 919-926.

Berger, M., Biasin, E., Saglio, F., & Fagioli, F. (2008). Innovative approaches to treat steroid-resistant or steroid refractory GVHD. Bone marrow transplantation, 42(2), S101-S105.

Bergmann, A. K., Grace, R. F., & Neufeld, E. J. (2010). Genetic studies in pediatric ITP: outlook, feasibility, and requirements. Annals of hematology, 89(Suppl 1), 95-103.

Bernin, H., & Lotter, H. (2014). Sex bias in the outcome of human tropical infectious diseases: influence of steroid hormones. The Journal of infectious diseases, 209(suppl_3), S107-S113.

Bianchi, D. W., Zickwolf, G. K., Weil, G. J., Sylvester, S., & DeMaria, M. A. (1996). Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum. Proceedings of the National Academy of Sciences, 93(2), 705-708.

Björklund, Å. K., Ekman, D., & Elofsson, A. (2006). Expansion of protein domain repeats. PLoS computational biology, 2(8), e114.

Blanchard, N., Lankar, D., Faure, F., Regnault, A., Dumont, C., Raposo, G., & Hivroz, C. (2002). TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/ζ complex. The Journal of Immunology, 168(7), 3235-3241.

Blazar, B. R., Murphy, W. J., & Abedi, M. (2012). Advances in graft-versus-host disease biology and therapy. Nature reviews immunology, 12(6), 443-458.

Blum, S., Ji, Y., Pennisi, D., Li, Z., Leo, P., McCombe, P., & Brown, M. A. (2018). Genome-wide association study in Guillain-Barre syndrome. Journal of Neuroimmunology, 323, 109-114.

Bonnet, D., Warren, E. H., Greenberg, P. D., Dick, J. E., & Riddell, S. R. (1999). CD8+ minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells. Proceedings of the National Academy of Sciences, 96(15), 8639-8644.

Bohring, C., Krause, E., Habermann, B., & Krause, W. (2001). Isolation and identification of sperm membrane antigens recognized by antisperm antibodies, and their possible role in immunological infertility disease. Molecular human reproduction, 7(2), 113-118.

Bournazos, S., Gupta, A., & Ravetch, J. V. (2020). The role of IgG Fc receptors in antibody-dependent enhancement. Nature Reviews Immunology, 20(10), 633-643.

Bracamonte-Baran, W., & Čiháková, D. (2017). Cardiac autoimmunity: myocarditis. The Immunology of Cardiovascular Homeostasis and Pathology, 187-221.

Brambatti, M., Matassini, M. V., Adler, E. D., Klingel, K., Camici, P. G., & Ammirati, E. (2017). Eosinophilic myocarditis: characteristics, treatment, and outcomes. Journal of the American College of Cardiology, 70(19), 2363-2375.

Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D. S., ... & Zychlinsky, A. (2004). Neutrophil extracellular traps kill bacteria. science, 303(5663), 1532-1535.

Carmona, F. D., Gonzalez-Gay, M. A., & Martín, J. (2014). Genetic component of giant cell arteritis. Rheumatology, 53(1), 6-18.

Chamley, L. W., & Clarke, G. N. (2007, June). Antisperm antibodies and conception. In Seminars in immunopathology (Vol. 29, pp. 169-184). Springer-Verlag.

Chen, J., & Chopp, M. (2018). Exosome therapy for stroke. Stroke, 49(5), 1083-1090.

Chih-Hao, C., & Reeves, W. H. (1992). Recognition of multiple epitopes in the coiled-coil domain of lamin B by human autoantibodies. Molecular immunology, 29(9), 1055-1064.

Chiu, I., Davis, D. M., & Strominger, J. L. (1999). Trafficking of spontaneously endocytosed MHC proteins. Proceedings of the National Academy of Sciences, 96(24), 13944-13949.

Cincinelli, G., Generali, E., Dudam, R., Ravindran, V., & Selmi, C. (2018). Why women or why not men? sex and autoimmune diseases. Indian Journal of rheumatology, 13(1), 44-50.

Coassin, N. A., & Kline, D. L. (1957). Radiophosphorus measurement of the lifespan of lymphocytes in the rabbit. American Journal of Physiology-Legacy Content, 190(1), 147-151.

Cooper Jr, L. T. (2009). Myocarditis. New England Journal of Medicine, 360(15), 1526-1538.

Cutler, C., Miklos, D., Kim, H. T., Treister, N., Woo, S. B., Bienfang, D., ... & Alyea, E. (2006). Rituximab for steroid-refractory chronic graft-versus-host disease. Blood, 108(2), 756-762.

D'Andrea, L. D., & Regan, L. (2003). TPR proteins: the versatile helix. Trends in biochemical sciences, 28(12), 655-662.

Darrah, E., & Andrade, F. (2013). NETs: the missing link between cell death and systemic autoimmune diseases?. Frontiers in immunology, 3, 428.

D’Cruz, O. J., Haas Jr, G. G., & Reichlin, M. (1994). Autoantibodies to decondensed sperm nuclear deoxyribonucleic acid in patients with antisperm antibodies and systemic lupus erythematosus detected by immunofluorescence flow cytometry. Fertility and sterility, 62(4), 834-844.

De Bari, C. (2015). Are mesenchymal stem cells in rheumatoid arthritis the good or bad guys?. Arthritis research & therapy, 17, 1-9.

DiLillo, D. J., Hamaguchi, Y., Ueda, Y., Yang, K., Uchida, J., Haas, K. M., ... & Tedder, T. F. (2008). Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice. The Journal of Immunology, 180(1), 361-371.

Dobson, R., & Giovannoni, G. (2019). Multiple sclerosis–a review. European journal of neurology, 26(1), 27-40.

Dohle, G. R., Smit, M., & Weber, R. F. A. (2003). Androgens and male fertility. World journal of urology, 21(5), 341-345.

Dohlman, J. G., Lupas, A., & Carson, M. (1993). Long charge-rich α-helices in systemic autoantigens. Biochemical and biophysical research communications, 195(2), 686-696.

Donadio, J. V., & Grande, J. P. (2002). IgA nephropathy. New England Journal of Medicine, 347(10), 738-748.

Dorak, M. T., & Karpuzoglu, E. (2012). Gender differences in cancer susceptibility: an inadequately addressed issue. Frontiers in genetics, 3, 268.

Dubey, D., Pittock, S. J., Kelly, C. R., McKeon, A., Lopez‐Chiriboga, A. S., Lennon, V. A., ... & Flanagan, E. P. (2018). Autoimmune encephalitis epidemiology and a comparison to infectious encephalitis. Annals of neurology, 83(1), 166-177.

Efthimiou, P., Kontzias, A., Hur, P., Rodha, K., Ramakrishna, G. S., & Nakasato, P. (2021, August). Adult-onset Still's disease in focus: Clinical manifestations, diagnosis, treatment, and unmet needs in the era of targeted therapies. In Seminars in arthritis and rheumatism (Vol. 51, No. 4, pp. 858-874). WB Saunders.

Fink, S. L., & Cookson, B. T. (2005). Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infection and immunity, 73(4), 1907-1916.

Finnegan, A., Ashaye, S., & Hamel, K. M. (2012). B effector cells in rheumatoid arthritis and experimental arthritis. Autoimmunity, 45(5), 353-363.

Fitzpatrick, F., Lepault, F., Homo-Delarche, F., Bach, J. F., & Dardenne, M. (1991). Influence of castration, alone or combined with thymectomy, on the development of diabetes in the nonobese diabetic mouse. Endocrinology, 129(3), 1382-1390.

Franklin, R. J., & Ffrench-Constant, C. (2017). Regenerating CNS myelin—from mechanisms to experimental medicines. Nature Reviews Neuroscience, 18(12), 753-769.

Friedrich, P., Guerra-García, P., Stetson, A., Duncan, C., & Lehmann, L. (2018). Young female donors do not increase the risk of graft-versus-host disease or impact overall outcomes in pediatric HLA-matched sibling hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation, 24(1), 96-102.

Fu, X., Liu, G., Halim, A., Ju, Y., Luo, Q., & Song, A. G. Mesenchymal stem cell migration and tissue repair. Cells. 2019; 8 (8): 784.

Fugazzola, L., Cirello, V., & Beck-Peccoz, P. (2012). Microchimerism and endocrine disorders. The Journal of Clinical Endocrinology, 97(5), 1452-1461.

Gaipl, U. S., Kuhn, A., Sheriff, A., Munoz, L. E., Franz, S., Voll, R. E., ... & Herrmann, M. (2006). Clearance of apoptotic cells in human SLE. Apoptosis and Its Relevance to Autoimmunity, 9, 173-187.

Gallardo, D., Aróstegui, J. I., Balas, A., Torres, A., Caballero, D., Carreras, E., ... & GvHD Subcommittee of the GETH (Grupo Español de trasplante hemapoyético. (2001). Disparity for the minor histocompatibility antigen HA‐1 is associated with an increased risk of acute graft‐versus‐host disease (GvHD) but it does not affect chronic GvHD incidence, disease‐free survival or overall survival after allogeneic human leucocyte antigen‐identical sibling donor transplantation. British Journal of Haematology, 114(4), 931-936.

Gao, F., Chiu, S. M., Motan, D. A. L., Zhang, Z., Chen, L., Ji, H. L., ... & Lian, Q. (2016). Mesenchymal stem cells and immunomodulation: current status and future prospects. Cell death & disease, 7(1), e2062-e2062.

Gentile, I., Bonadies, G., Buonomo, A. R., Minei, G., Borrelli, F., Foggia, M., ... & Borgia, G. (2013). Resolution of autoimmune thrombocytopenia associated with raltegravir use in an HIV-positive patient. Platelets, 24(7), 574-577.

González-Gay, M. A., Matteson, E. L., & Castañeda, S. (2017). Polymyalgia rheumatica. The Lancet, 390(10103), 1700-1712.

Graham, J. B., Canniff, N. P., & Hebert, D. N. (2019). TPR-containing proteins control protein organization and homeostasis for the endoplasmic reticulum. Critical reviews in biochemistry and molecular biology, 54(2), 103-118.

Gravholt, C. H., Viuff, M. H., Brun, S., Stochholm, K., & Andersen, N. H. (2019). Turner syndrome: mechanisms and management. Nature Reviews Endocrinology, 15(10), 601-614.

Grossmann, B., Saur, S., Rall, K., Pecher, A. C., Hübner, S., Henes, J., & Henes, M. (2020). Prevalence of autoimmune disease in women with premature ovarian failure. The European Journal of Contraception & Reproductive Health Care, 25(1), 72-75.

Groth, K. A., Skakkebæk, A., Høst, C., Gravholt, C. H., & Bojesen, A. (2013). Klinefelter syndrome—a clinical update. The Journal of Clinical Endocrinology & Metabolism, 98(1), 20-30.

Grumet, F. C., Hiraki, D. D., Brown, B. W., Zehnder, J. L., Zacks, E. S., Draksharapu, A., ... & Negrin, R. S. (2001). CD31 mismatching affects marrow transplantation outcome. Biology of Blood and Marrow Transplantation, 7(9), 503-512.

Gudjonsson, J. E., & Elder, J. T. (2007). Psoriasis: epidemiology. Clinics in dermatology, 25(6), 535-546.

Hanafusa, T., Pujol-Borrell, R., Chiovato, L., Doniach, D., Pujol-Borrell, R., Russell, R. C. G., & Bottazzo, G. F. (1983). Aberrant expression of HLA-DR antigen on thyrocytes in Graves’ disease: relevance for autoimmunity. The Lancet, 322(8359), 1111-1115.

Hanayama, R., Tanaka, M., Miyasaka, K., Aozasa, K., Koike, M., Uchiyama, Y., & Nagata, S. (2004). Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science, 304(5674), 1147-1150.

Hashimoto H. 1912 Zur Kenntniss der lymphomatösen Veränderung der schilddrüse (struma lymphomatosa). arch Klin Chir 97: 219-248.

Hayashida, K., Omagari, K., Masuda, J.I., Hazama, H., Kadokawa, Y., Ohba, K., and Kohno, S. (2005). The sperm mitochondria-specific translocator has a key role in maternal mitochondrial inheritance, Cell Biol. Int. 29, 472–481.

Hayashida, K., Omagari, K., Masuda, J.I., and Kohno, S. (2008). An integrase of endogenous retrovirus is involved in maternal mitochondrial DNA inheritance of the mouse. Biochem. Biophys. Res. Commun. 366, 206–211.

Hayashida, K., and Kohno, S. (2009) Hybrid male sterility is caused by mitochondrial DNA deletion. Mol. Biol. Rep. 36, 1365-1369.

Hayashida, K. (2022) On The Origin of Speciation. EcoEvoRxiv.org

Hayter, S. M., & Cook, M. C. (2012). Updated assessment of the prevalence, spectrum and case definition of autoimmune disease. Autoimmunity reviews, 11(10), 754-765.

Hennessey, J. V. (2011). Riedel's thyroiditis: a clinical review. The Journal of Clinical Endocrinology & Metabolism, 96(10), 3031-3041.

Herrero-Cervera, A., Soehnlein, O., & Kenne, E. (2022). Neutrophils in chronic inflammatory diseases. Cellular & Molecular Immunology, 19(2), 177-191.

Hiepe, F., Dörner, T., Hauser, A. E., Hoyer, B. F., Mei, H., & Radbruch, A. (2011). Long-lived autoreactive plasma cells drive persistent autoimmune inflammation. Nature Reviews Rheumatology, 7(3), 170-178.

Hughes, R. A., & Cornblath, D. R. (2005). Guillain-barre syndrome. The Lancet, 366(9497), 1653-1666.

Ichiryu, N., & Fairchild, P. J. (2013). Immune privilege of stem cells. Embryonic Stem Cell Immunobiology: Methods and Protocols, 1-16.

Inoue, D., Yoshida, K., Yoneda, N., Ozaki, K., Matsubara, T., Nagai, K., ... & Zen, Y. (2015). IgG4-related disease: dataset of 235 consecutive patients. Medicine, 94(15).

Jabet, C., Sprague, E. R., VanDemark, A. P., & Wolberger, C. (2000). Characterization of the N-terminal Domain of the Yeast Transcriptional Repressor Tup1: PROPOSAL FOR AN ASSOCIATION MODEL OF THE REPRESSOR COMPLEX Tup1· Ssn6. Journal of Biological Chemistry, 275(12), 9011-9018.

Jacobsohn, D. A., & Vogelsang, G. B. (2007). Acute graft versus host disease. Orphanet journal of rare diseases, 2, 1-9.

Jagasia, M. H., Greinix, H. T., Arora, M., Williams, K. M., Wolff, D., Cowen, E. W., ... & Flowers, M. E. (2015). National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. The 2014 Diagnosis and Staging Working Group report. Biology of Blood and Marrow Transplantation, 21(3), 389-401.

Jin, H., Arase, N., Hirayasu, K., Kohyama, M., Suenaga, T., Saito, F., ... & Arase, H. (2014). Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility. Proceedings of the National Academy of Sciences, 111(10), 3787-3792.

Jones, E. Y., Fugger, L., Strominger, J. L., & Siebold, C. (2006). MHC class II proteins and disease: a structural perspective. Nature Reviews Immunology, 6(4), 271-282.

Jørgensen, K. T., Rostgaard, K., Bache, I., Biggar, R. J., Nielsen, N. M., Tommerup, N., & Frisch, M. (2010). Autoimmune diseases in women with Turner's syndrome. Arthritis & Rheumatism, 62(3), 658-666.

Kahn, D. A., & Baltimore, D. (2010). Pregnancy induces a fetal antigen-specific maternal T regulatory cell response that contributes to tolerance. Proceedings of the National Academy of Sciences, 107(20), 9299-9304.

Kamisawa, T. (2023). Epidemiology of autoimmune pancreatitis. The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, 533-539.

Khodadadi, L., Cheng, Q., Radbruch, A., & Hiepe, F. (2019). The maintenance of memory plasma cells. Frontiers in immunology, 721.

Kim, H. T., Zhang, M. J., Woolfrey, A. E., Martin, A. S., Chen, J., Saber, W., ... & Eapen, M. (2016). Donor and recipient sex in allogeneic stem cell transplantation: what really matters. Haematologica, 101(10), 1260.

Kirshenbaum, M., & Orvieto, R. (2019). Premature ovarian insufficiency (POI) and autoimmunity-an update appraisal. Journal of assisted reproduction and genetics, 36, 2207-2215.

Kobayashi, H., & Choyke, P. L. (2019). Near-infrared photoimmunotherapy of cancer. Accounts of chemical research, 52(8), 2332-2339.

Kollman, C., Howe, C. W., Anasetti, C., Antin, J. H., Davies, S. M., Filipovich, A. H., ... & Confer, D. L. (2001). Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood, The Journal of the American Society of Hematology, 98(7), 2043-2051.

Krishna, M., & Nadler, S. G. (2016). Immunogenicity to biotherapeutics–the role of anti-drug immune complexes. Frontiers in immunology, 7, 21.

Kuzmina, Z., Gounden, V., Curtis, L., Avila, D., Rnp, T. T., Baruffaldi, J., ... & Pavletic, S. Z. (2015). Clinical significance of autoantibodies in a large cohort of patients with chronic graft‐versus‐host disease defined by NIH criteria. American journal of hematology, 90(2), 114-119.

Lai, W. L., Yeh, T. H., Chen, P. M., Chan, C. K., Chiang, W. C., Chen, Y. M., ... & Tsai, T. J. (2015). Membranous nephropathy: a review on the pathogenesis, diagnosis, and treatment. Journal of the Formosan Medical Association, 114(2), 102-111.

Lai, X. L., Xiong, W. J., Li, L. S., Lan, M. F., Zhang, J. X., Zhou, Y. T., ... & Duan, X. (2023). Zinc deficiency compromises the maturational competence of porcine oocyte by inducing mitophagy and apoptosis. Ecotoxicology and Environmental Safety, 252, 114593.

Lambert, N. C., Erickson, T. D., Yan, Z., Pang, J. M., Guthrie, K. A., Furst, D. E., & Nelson, J. L. (2004). Quantification of maternal microchimerism by HLA‐specific real‐time polymerase chain reaction: studies of healthy women and women with scleroderma. Arthritis & Rheumatism, 50(3), 906-914.

Lee, H. Y., & Hong, I. S. (2017). Double‐edged sword of mesenchymal stem cells: cancer‐promoting versus therapeutic potential. Cancer science, 108(10), 1939-1946.

Lei, L., Su, J., Chen, J., Chen, W., Chen, X., & Peng, C. (2019). Abnormal serum copper and zinc levels in patients with psoriasis: A meta-analysis. Indian journal of dermatology, 64(3), 224.

 

Leung, P. S., Rossaro, L., Davis, P. A., Park, O., Tanaka, A., Kikuchi, K., ... & Acute Liver Failure Study Group. (2007). Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis. Hepatology, 46(5), 1436-1442.

Li, M., & Ikehara, S. (2013). Bone-marrow-derived mesenchymal stem cells for organ repair. Stem cells international, 2013.

Li, W., Deng, R., Jing, X., Chen, J., Yang, D., & Shen, J. (2020). Acteoside ameliorates experimental autoimmune encephalomyelitis through inhibiting peroxynitrite-mediated mitophagy activation. Free Radical Biology and Medicine, 146, 79-91.

Li, X., Gibson, A. W., & Kimberly, R. P. (2014). Human FcR polymorphism and disease. Fc Receptors, 275-302.

Liang, B., Peng, P., Chen, S., Li, L., Zhang, M., Cao, D., ... & Shen, K. (2013). Characterization and proteomic analysis of ovarian cancer-derived exosomes. Journal of proteomics, 80, 171-182.

Lin, Y. J., Wan, L., Wu, J. Y., Sheu, J. C., Lin, C. W., Lan, Y. C., ... & Tsai, F. J. (2009). HLA–E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 60(2), 604-610.

Linscheid, C., & Petroff, M. G. (2013). Minor histocompatibility antigens and the maternal immune response to the fetus during pregnancy. American Journal of Reproductive Immunology, 69(4), 304-314.

Lissauer, D., Piper, K., Goodyear, O., Kilby, M. D., & Moss, P. A. (2012). Fetal-specific CD8+ cytotoxic T cell responses develop during normal human pregnancy and exhibit broad functional capacity. The Journal of Immunology, 189(2), 1072-1080.

Liu, J., Ding, Y., Liu, Z., & Liang, X. (2020). Senescence in mesenchymal stem cells: functional alterations, molecular mechanisms, and rejuvenation strategies. Frontiers in Cell and Developmental Biology, 8, 258.

Loren, A. W., Bunin, G. R., Boudreau, C., Champlin, R. E., Cnaan, A., Horowitz, M. M., ... & Porter, D. L. (2006). Impact of donor and recipient sex and parity on outcomes of HLA-identical sibling allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation, 12(7), 758-769.

Lozada-Nur, F., & Miranda, C. (1997, December). Oral lichen planus: epidemiology, clinical characteristics, and associated diseases. In Seminars in cutaneous Medicine and Surgery (Vol. 16, No. 4, pp. 273-277). WB Saunders.

Lucas, P. L., & Rose, N. R. (1978). Immunological consequences of vasectomy: I. Prospective study through one-year postvasectomy. Archives of Andrology, 1(3), 249-255.

Magna, M., & Pisetsky, D. S. (2015). The role of cell death in the pathogenesis of SLE: is pyroptosis the missing link?. Scandinavian journal of immunology, 82(3), 218-224.

Mahar, M., & Cavalli, V. (2018). Intrinsic mechanisms of neuronal axon regeneration. Nature Reviews Neuroscience, 19(6), 323-337.

Mahmood, U., & O’Donoghue, K. (2014). Microchimeric fetal cells play a role in maternal wound healing after pregnancy. Chimerism, 5(2), 40-52.

Markle, J. G., Frank, D. N., Mortin-Toth, S., Robertson, C. E., Feazel, L. M., Rolle-Kampczyk, U., ... & Danska, J. S. (2013). Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity. Science, 339(6123), 1084-1088.

Maslinska, M., Dmowska-Chalaba, J., & Jakubaszek, M. (2022). The role of IgG4 in autoimmunity and rheumatic diseases. Frontiers in Immunology, 12, 787422.

Mathews, J. D., Skegg, D. C., Vessey, M. P., Konice, M., Holborow, E. J., & Guillebaud, J. (1976). Weak autoantibody reactions to antigens other than sperm after vasectomy. Br Med J, 2(6048), 1359-1360.

Matzaraki, V., Kumar, V., Wijmenga, C., & Zhernakova, A. (2017). The MHC locus and genetic susceptibility to autoimmune and infectious diseases. Genome biology, 18(1), 1-21.

Maurizy, C., Quinternet, M., Abel, Y., Verheggen, C., Santo, P. E., Bourguet, M., ... & Bertrand, E. (2018). The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones. Nature Communications, 9(1), 2093.

Mauro, D., Thomas, R., Guggino, G., Lories, R., Brown, M. A., & Ciccia, F. (2021). Ankylosing spondylitis: an autoimmune or autoinflammatory disease?. Nature Reviews Rheumatology, 17(7), 387-404.

Maywald, M., Wang, F., & Rink, L. (2018). The intracellular free zinc level is vital for treg function and a feasible tool to discriminate between treg and activated Th cells. International Journal of Molecular Sciences, 19(11), 3575.

McKenna, W. J., Maron, B. J., & Thiene, G. (2017). Classification, epidemiology, and global burden of cardiomyopathies. Circulation research, 121(7), 722-730.

Miklos, D. B., Kim, H. T., Miller, K. H., Guo, L., Zorn, E., Lee, S. J., ... & Ritz, J. (2005). Antibody responses to HY minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission. Blood, 105(7), 2973-2978.

Morrison, S. J., & Scadden, D. T. (2014). The bone marrow niche for haematopoietic stem cells. Nature, 505(7483), 327-334.

Muñoz, L. E., Lauber, K., Schiller, M., Manfredi, A. A., & Herrmann, M. (2010). The role of defective clearance of apoptotic cells in systemic autoimmunity. Nature Reviews Rheumatology, 6(5), 280-289.

Murray, J., Stringer, J., & Hutt, D. (2018). Graft-versus-host disease (GvHD). The European blood and marrow transplantation textbook for nurses: Under the auspices of EBMT, 221-251.

Nagata, S., Hanayama, R., & Kawane, K. (2010). Autoimmunity and the clearance of dead cells. Cell, 140(5), 619-630.

Nakasone, H., Tian, L., Sahaf, B., Kawase, T., Schoenrock, K., Perloff, S., ... & Miklos, D. B. (2015). Allogeneic HY antibodies detected 3 months after female-to-male HCT predict chronic GVHD and nonrelapse mortality in humans. Blood, The Journal of the American Society of Hematology, 125(20), 3193-3201.

Navarro‐Cobos, M. J., Balaton, B. P., & Brown, C. J. (2020, June). Genes that escape from X‐chromosome inactivation: Potential contributors to Klinefelter syndrome. In American Journal of Medical Genetics Part C: Seminars in Medical Genetics (Vol. 184, No. 2, pp. 226-238). Hoboken, USA: John Wiley & Sons, Inc..

Naz, R. K., & Menge, A. C. (1994). Antisperm antibodies: origin, regulation, and sperm reactivity in human infertility. Fertility and sterility, 61(6), 1001-1013.

Nche, E. N., & Amer, R. (2020). Lens-induced uveitis: an update. Graefe's Archive for Clinical and Experimental Ophthalmology, 258, 1359-1365.

Nelson, J. L., Gillespie, K. M., Lambert, N. C., Stevens, A. M., Loubiere, L. S., Rutledge, J. C., ... & Gale, E. A. (2007). Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet β cell microchimerism. Proceedings of the National Academy of Sciences, 104(5), 1637-1642.

Nelson, J. L., Furst, D. E., Maloney, S., Gooley, T., Evans, P. C., Smith, A., ... & Bianchi, D. W. (1998). Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. The Lancet, 351(9102), 559-562.

Nelson, J. L. (2012). The otherness of self: microchimerism in health and disease. Trends in immunology, 33(8), 421-427.

Ngo, S. T., Steyn, F. J., & McCombe, P. A. (2014). Gender differences in autoimmune disease. Frontiers in neuroendocrinology, 35(3), 347-369.

Nielsen, H. S., Wu, F., Aghai, Z., Steffensen, R., Van Halteren, A. G., Spierings, E., ... & Goulmy, E. (2010). HY antibody titers are increased in unexplained secondary recurrent miscarriage patients and associated with low male: female ratio in subsequent live births. Human Reproduction, 25(11), 2745-2752.

Parikh-Patel, A., Gold, E., Utts, J., & Gershwin, M. E. (2002). The association between gravidity and primary biliary cirrhosis. Annals of epidemiology, 12(4), 264-272.

Pavletic, S. Z., Carter, S. L., Kernan, N. A., Henslee-Downey, J., Mendizabal, A. M., Papadopoulos, E., ... & members of the National Heart, Lung, and Blood Institute Unrelated Donor Marrow Transplantation Trial. (2005). Influence of T-cell depletion on chronic graft-versus-host disease: results of a multicenter randomized trial in unrelated marrow donor transplantation. Blood, 106(9), 3308-3313.

Pawelec, G. (2018). Age and immunity: what is “immunosenescence”?. Experimental gerontology, 105, 4-9.

Pelletier, R. M., & Byers, S. W. (1992). The blood‐testis barrier and Sertoli cell junctions: Structural considerations. Microscopy research and technique, 20(1), 3-33.

Pender, M. P. (2003). Infection of autoreactive B lymphocytes with EBV, causing chronic autoimmune diseases. Trends in immunology, 24(11), 584-588.

Petroff, M. G. (2005). Immune interactions at the maternal–fetal interface. Journal of reproductive immunology, 68(1-2), 1-13.

Pickles, S., Vigié, P., & Youle, R. J. (2018). Mitophagy and quality control mechanisms in mitochondrial maintenance. Current Biology, 28(4), R170-R185.

Popli, R., Sahaf, B., Nakasone, H., Lee, J. Y. Y., & Miklos, D. B. (2014). Clinical impact of HY alloimmunity. Immunologic research, 58, 249-258.

Pritz, T., Lair, J., Ban, M., Keller, M., Weinberger, B., Krismer, M., & Grubeck‐Loebenstein, B. (2015). Plasma cell numbers decrease in bone marrow of old patients. European journal of immunology, 45(3), 738-746.

Quattrocchio, G., & Roccatello, D. (2016). IgG4-related nephropathy. Journal of Nephrology, 29(4), 487-493.

Rajabi, F., Drake, L. A., Senna, M. M., & Rezaei, N. (2018). Alopecia areata: a review of disease pathogenesis. British Journal of Dermatology, 179(5), 1033-1048.

Rakar, S., Sinagra, Sinagra G., Di Lenarda, A., Poletti, A., Bussani, R., Silvestri, F., ... & Heart Muscle Disease Study Group. (1997). Epidemiology of dilated cardiomyopathy: a prospective post-mortem study of 5252 necropsies. European heart journal, 18(1), 117-123.

Randolph, S. S., Gooley, T. A., Warren, E. H., Appelbaum, F. R., & Riddell, S. R. (2004). Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants. Blood, 103(1), 347-352.

Raposo, G., & Stoorvogel, W. (2013). Extracellular vesicles: exosomes, microvesicles, and friends. Journal of Cell Biology, 200(4), 373-383.

Remberger, M., Kumlien, G., Aschan, J., Barkholt, L., Hentschke, P., Ljungman, P., ... & Ringdén, O. (2002). Risk factors for moderate-to-severe chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Biology of blood and marrow transplantation, 8(12), 674-682.

Rialland, P., Lankar, D., Raposo, G., Bonnerot, C., & Hubert, P. (2006). BCR‐bound antigen is targeted to exosomes in human follicular lymphoma B‐cells 1. Biology of the Cell, 98(8), 491-501.

Rieux-Laucat, F., Fischer, A., & Le Deist, F. (2003). Cell-death signaling and human disease. Current opinion in immunology, 15(3), 325-331.

Rosenkranz, E., Metz, C. H., Maywald, M., Hilgers, R. D., Weßels, I., Senff, T., ... & Rink, L. (2016). Zinc supplementation induces regulatory T cells by inhibition of Sirt‐1 deacetylase in mixed lymphocyte cultures. Molecular nutrition & food research, 60(3), 661-671.

Sahaf, B., Yang, Y., Arai, S., Herzenberg, L. A., Herzenberg, L. A., & Miklos, D. B. (2013). H–Y antigen-binding B cells develop in male recipients of female hematopoietic cells and associate with chronic graft vs. host disease. Proceedings of the National Academy of Sciences, 110(8), 3005-3010.

Sanna, A., Firinu, D., Zavattari, P., & Valera, P. (2018). Zinc status and autoimmunity: a systematic review and meta-analysis. Nutrients, 10(1), 68.

Sandyk, R. (1993). Multiple sclerosis: the role of puberty and the pineal gland in its pathogenesis. International journal of neuroscience, 68(3-4), 209-225.

Sarma, J. V., & Ward, P. A. (2011). The complement system. Cell and tissue research, 343(1), 227-235.

Sasaki, M., Miyakoshi, M., Sato, Y., & Nakanuma, Y. (2010). Autophagy mediates the process of cellular senescence characterizing bile duct damages in primary biliary cirrhosis. Laboratory Investigation, 90(6), 835-843.

Scofield, R. H., Bruner, G. R., Namjou, B., Kimberly, R. P., Ramsey‐Goldman, R., Petri, M., ... & Harley, J. B. (2008). Klinefelter's syndrome (47, XXY) in male systemic lupus erythematosus patients: support for the notion of a gene‐dose effect from the X chromosome. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 58(8), 2511-2517.

Seissler, N., Schmitt, E., Hug, F., Sommerer, C., Zeier, M., Schaier, M., & Steinborn, A. (2012). Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR+-Treg-cells in transplanted patients. Transplant immunology, 27(4), 157-161.

Seminog, O. O., Seminog, A. B., Yeates, D., & Goldacre, M. J. (2015). Associations between Klinefelter’s syndrome and autoimmune diseases: English national record linkage studies. Autoimmunity, 48(2), 125-128.

Sener, A. G., & Afsar, I. (2012). Infection and autoimmune disease. Rheumatology international, 32, 3331-3338.

Shah, S., Wu, E., Rao, V. K., & Tarrant, T. K. (2014). Autoimmune lymphoproliferative syndrome: an update and review of the literature. Current allergy and asthma reports, 14, 1-5.

Shrivastava, S., Naik, R., Suryawanshi, H., & Gupta, N. (2019). Microchimerism: A new concept. Journal of oral and maxillofacial pathology: JOMFP, 23(2), 311.

Silina, K., Zayakin, P., Kalnina, Z., Ivanova, L., Meistere, I., Endzelinš, E., ... & Line, A. (2011). Sperm-associated antigens as targets for cancer immunotherapy: expression pattern and humoral immune response in cancer patients. Journal of immunotherapy, 34(1), 28-44.

Smith, A. J., Bustamante-Marin, X. M., Yin, W., Sears, P. R., Herring, L. E., Dicheva, N. N., ... & Ostrowski, L. E. (2022). The role of SPAG1 in the assembly of axonemal dyneins in human airway epithelia. Journal of Cell Science, 135(6), jcs259512.

Smits, H. H., & Yazdanbakhsh, M. (2007). Chronic helminth infections modulate allergen‐specific immune responses: protection against development of allergic disorders?. Annals of medicine, 39(6), 428-439.

Soares, P. M. F., Borba, E. F., Bonfa, E., Hallak, J., Corrêa, A. L., & Silva, C. A. A. (2007). Gonad evaluation in male systemic lupus erythematosus. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 56(7), 2352-2361.

Song, R., Ro, S., Michaels, J. D., Park, C., McCarrey, J. R., & Yan, W. (2009). Many X-linked microRNAs escape meiotic sex chromosome inactivation. Nature genetics, 41(4), 488-493.

Sotolongo, J. R. (1982). Immunological effects of vasectomy. The Journal of Urology, 127(6), 1063-1066.

Stagnaro-Green, A. (2004). Postpartum thyroiditis. Best Practice & Research Clinical Endocrinology & Metabolism, 18(2), 303-316.

Stanley, P. (2011). Golgi glycosylation. Cold Spring Harbor perspectives in biology, 3(4), a005199.

Stassen, P. M., Cohen-Tervaert, J. W., Lems, S. P., Hepkema, B. G., Kallenberg, C. G., & Stegeman, C. A. (2009). HLA-DR4, DR13 (6) and the ancestral haplotype A1B8DR3 are associated with ANCA-associated vasculitis and Wegener's granulomatosis. Rheumatology, 48(6), 622-625.

Stebbing, J., Savage, P., Patterson, S., & Gazzard, B. (2004). All for CD91 and CD91 for all. Journal of Antimicrobial Chemotherapy, 53(1), 1-3.

Stern, M., Brand, R., De Witte, T., Sureda, A., Rocha, V., Passweg, J., ... & Gratwohl, A. (2008). Female-versus-male alloreactivity as a model for minor histocompatibility antigens in hematopoietic stem cell transplantation. American journal of transplantation, 8(10), 2149-2157.

Stone, J. H., Zen, Y., & Deshpande, V. (2012). IgG4-related disease. New England Journal of Medicine, 366(6), 539-551.

Straubel, D., Thielitz, A., Reinhold, A., Grüngreiff, K., & Reinhold, D. (2018). Combined treatment with zinc aspartate and intravenous immunoglobulins (IVIGs) ameliorates experimental autoimmune encephalomyelitis (EAE). Journal of Immunology Research, 2018.

Strauss, H. M., & Keller, S. (2008). Pharmacological interference with protein-protein interactions mediated by coiled-coil motifs. Protein-Protein Interactions as New Drug Targets, 461-482.

Sun, L., Edelmann, F. T., Kaiser, C. J., Papsdorf, K., Gaiser, A. M., & Richter, K. (2012). The lid domain of Caenorhabditis elegans Hsc70 influences ATP turnover, cofactor binding and protein folding activity. PLoS One, 7(3), e33980.

Takai, T. (2005). Fc receptors and their role in immune regulation and autoimmunity. Journal of clinical immunology, 25, 1-18.

Tanaka, K., Ogino, R., Yamakawa, S., Suda, S., & Hayashida, K. (2022). Role and function of mesenchymal stem cells on fibroblast in cutaneous wound healing. Biomedicines, 10(6), 1391.

Tan Sardjono, C., Mottram, P. L., & Hogarth, P. M. (2003). The role of FcγRIIa as an inflammatory mediator in rheumatoid arthritis and systemic lupus erythematosus. Immunology and cell biology, 81(5), 374-381.

Tenembaum, S., Chitnis, T., Ness, J., & Hahn, J. S. (2007). Acute disseminated encephalomyelitis. Neurology, 68(16 suppl 2), S23-S36.

Terao, C., Yoshifuji, H., & Mimori, T. (2014). Recent advances in T akayasu arteritis. International journal of rheumatic diseases, 17(3), 238-247.

Tony, H. P., Burmester, G., Schulze-Koops, H., Grunke, M., Henes, J., Kötter, I., ... & Dörner, T. (2011). Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID). Arthritis research & therapy, 13(3), 1-14.

Trivedi, P. J., Bowlus, C. L., Yimam, K. K., Razavi, H., & Estes, C. (2022). Epidemiology, natural history, and outcomes of primary sclerosing cholangitis: a systematic review of population-based studies. Clinical Gastroenterology and Hepatology, 20(8), 1687-1700.

Tsubota, K., Fujita, H., Tsuzaka, K., & Takeuchi, T. (2000). Mikulicz’s disease and Sjogren’s syndrome. Investigative ophthalmology & visual science, 41(7), 1666-1673.

Tsuchiya, N., Kobayashi, S., Kawasaki, A., Kyogoku, C., Arimura, Y., Yoshida, M., ... & Hashimoto, H. (2003). Genetic background of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis: association of HLA-DRB1* 0901 with microscopic polyangiitis. The Journal of Rheumatology, 30(7), 1534-1540.

Tung, K. S., Cooke Jr, W. D., McCARTY, T. A., & Robitaille, P. (1976). Human sperm antigens and antisperm antibodies. II. Age-related incidence of antisperm antibodies. Clinical and Experimental Immunology, 25(1), 73.

Tyndall, A., & Dazzi, F. (2008). Chronic GVHD as an autoimmune disease. Best Practice & Research Clinical Haematology, 21(2), 281-289.

Usategui, A., Del Rey, M. J., & Pablos, J. L. (2011). Fibroblast abnormalities in the pathogenesis of systemic sclerosis. Expert Review of Clinical Immunology, 7(4), 491-498.

Uygur, A., & Lee, R. T. (2016). Mechanisms of cardiac regeneration. Developmental cell, 36(4), 362-374.

Vigorito, A. C., Campregher, P. V., Storer, B. E., Carpenter, P. A., Moravec, C. K., Kiem, H. P., ... & Flowers, M. E. (2009). Evaluation of NIH consensus criteria for classification of late acute and chronic GVHD. Blood, The Journal of the American Society of Hematology, 114(3), 702-708.

Virakul, S., Somparn, P., Pisitkun, T., van der Spek, P. J., Dalm, V. A., Paridaens, D., ... & Dik, W. A. (2021). Integrative analysis of proteomics and DNA methylation in orbital fibroblasts from graves’ ophthalmopathy. Frontiers in endocrinology, 11, 619989.

Walter, R. B., Milano, F., Brasky, T. M., & White, E. (2011). Long-term use of acetaminophen, aspirin, and other nonsteroidal anti-inflammatory drugs and risk of hematologic malignancies: results from the prospective Vitamins and Lifestyle (VITAL) study. Journal of clinical oncology, 29(17), 2424.

Wang, L., Wang, F. S., & Gershwin, M. E. (2015). Human autoimmune diseases: a comprehensive update. Journal of internal medicine, 278(4), 369-395.

Wang, Y. X., Zhu, W. J., & Jiang, H. (2013). Sperm exposure during menses is a risk factor for developing antisperm antibody (ASA) in female. Archives of gynecology and obstetrics, 288, 1145-1148.

Wraith, D. C., Goldman, M., & Lambert, P. H. (2003). Vaccination and autoimmune disease: what is the evidence?. The Lancet, 362(9396), 1659-1666.

Wu, D. J., & Adamopoulos, I. E. (2017). Autophagy and autoimmunity. Clinical Immunology, 176, 55-62.

Xia, M., Meng, G., Jiang, A., Chen, A., Dahlhaus, M., Gonzalez, P., ... & Wei, J. (2014). Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus. Oncotarget, 5(11), 3907.

Yamamoto, M., Takahashi, H., Sugai, S., & Imai, K. (2005). Clinical and pathological characteristics of Mikulicz's disease (IgG4-related plasmacytic exocrinopathy). Autoimmunity reviews, 4(4), 195-200.

Yamamoto, M., Takahashi, H., Ohara, M., Suzuki, C., Naishiro, Y., Yamamoto, H., ... & Imai, K. (2006). A new conceptualization for Mikulicz's disease as an IgG4-related plasmacytic disease. Modern Rheumatology, 16, 335-340.

Yang, S. K., Zhang, H. R., Shi, S. P., Zhu, Y. Q., Song, N., Dai, Q., ... & Zhang, H. (2020). The role of mitochondria in systemic lupus erythematosus: a glimpse of various pathogenetic mechanisms. Current Medicinal Chemistry, 27(20), 3346-3361.

Yanir, A. D., Hanson, I. C., Shearer, W. T., Noroski, L. M., Forbes, L. R., Seeborg, F. O., ... & Martinez, C. A. (2018). High incidence of autoimmune disease after hematopoietic stem cell transplantation for chronic granulomatous disease. Biology of Blood and Marrow Transplantation, 24(8), 1643-1650.

Yokoyama, A., Igarashi, K., Sato, T., Takagi, K., Otsuka, M., Shishido, Y., ... & Sugawara, A. (2014). Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex. Journal of Biological Chemistry, 289(26), 18152-18162.

Zeng, Y., Zhao, K., Oros Klein, K., Shao, X., Fritzler, M. J., Hudson, M., ... & Greenwood, C. M. (2021). Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals. Genes, 12(9), 1349.

Zhang, H. (2020). Impact of donor and recipient characteristics on graft-versus-host disease and survival in HLA-matched sibling hematopoietic stem cell transplantation. Transfusion and Apheresis Science, 59(3), 102743.

Zhou, X., Tan, F. K., Xiong, M., Arnett, F. C., & Feghali‐Bostwick, C. A. (2005). Monozygotic twins clinically discordant for scleroderma show concordance for fibroblast gene expression profiles. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 52(10), 3305-3314.

Zininga, T., Ramatsui, L., & Shonhai, A. (2018). Heat shock proteins as immunomodulants. Molecules, 23(11), 2846.