Verification of questionable information about the COVID-19 vaccines

抄録

Since the rollout of large-scale COVID-19 vaccination programs, misinformation has often been disseminated through social media, particularly regarding mRNA vaccines. Even scientists have sometimes exacerbated the problem and undermined public trust in health policies by proposing questionable theories. In this study, we present experimental and statistical analyses that address these claims. Animal experiments were conducted to evaluate the hypothesis that self-amplifying RNA vaccines can replicate and spread between individuals, a theory that our findings strongly refute. We also examined the claim that the presence of DNA contamination in mRNA vaccine formulations leads to the integration of DNA fragments into the genome, thereby altering gene function or expression to induce various adverse events, a theory that is also refuted by our findings. Additionally, we conducted statistical comparisons between mRNA and conventional influenza vaccines, challenging the narrative promoted by mainstream scientists and physicians that mRNA vaccines are categorically safer. Our findings underscore the need for scientists to rigorously investigate and transparently communicate about such claims, thereby helping to rebuild public trust in vaccination efforts.